Hmm, I think I just figured it out: 1. Open each region in the Sample Editor 2. In the Sample Editor > View pull down menu, click "Samples". The little window in the upper left hand corner of the Sample Editor window changes from 1 1 1 1 type display to 00000000 type sample display. 3. Drag the Anchor Point triangle to the right until the window reads "-1024", which in this case moves the region 1024 samples earlier in time. This is convenient in my case, where I know the buffer latency of the Mbox. To achieve single sample resolution, you have to zoom way in.